The cNT-proBNP test is a rapid quantitative test for the concentration of N-terminal pro B-type natriuretic peptide (NT-proBNP) in canine serum or plasma. Clinically, it is used mainly for the assistant diagnosis of canine heart failure.
🧪 Test principle
The test employs a quantitative double-antibody sandwich fluorescence immunoassay technique. The sample is mixed with the diluent and the mixture is dispensed into the well of the cartridge. NT-proBNP in the sample binds to a fluorescently labelled antibody, and the resulting complex is captured by the corresponding antigen immobilised on the detection line of the nitrocellulose membrane. The more analyte the sample contains, the more labelled antibody accumulates on the detection line and the stronger the measured signal. The concentration is reported in pmol/L.
📊 Detection range and interpretation
Detection range of the kit: 150–6000 pmol/L. Samples with values outside this range are reported as <150 pmol/L or >6000 pmol/L.
| Result (pmol/L) | Significance |
| ≤ 800 | Negative |
| > 800 | Abnormal |
The reference values shown are recommended — each laboratory should establish its own reference range. The final assessment is made by a veterinarian on the basis of the clinical picture and all available laboratory data.
The test is intended for use only with the Ozelle EHVT-50 multifunction veterinary analyzer.
